Angiomyofibroblastoma (AMF) is a rare, benign neoplasm commonly involving the vulvovaginal region, nearly always at the labia majora.

A 52 year-old premenopausal woman, presented with a large mass at the right vulva. The mass has been present for a year prior to presentation, but noted to be increasing in size. She denied any other symptoms such as pain or difficulty with micturition. Examination of the perineum revealed a 20×20 cm firm pedunculated mass, with stalk measuring 5 cm in diameter. A CT scan was performed and reported as a pedunculated vulva tumour with evidence of muscular fascia involvement.

In May 2015, we performed a wide local excision and right labia reconstruction. The mass consists of mainly fat tissues and vessels, weighing 1 kg. The 8 cm skin incision was repaired in layers and healed well during post-op review. She has been under our follow up and remains well with no recurrence to date.

Conclusion: AMF is usually painless and slow growing. Patients may tend to ignore or delay seeking medical attention, and may subsequently present later, when the mass is larger. After excluding other, more common, benign tumours of the vulva, AMF should be considered in the differential diagnoses even in the younger group of women. Complete excision is usually curative.